Inducible cancer model to study the molecular basis of host tumor cell interactions in vivo

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United States of America Patent

PATENT NO 6639121
SERIAL NO

09619247

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Abstract

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A non-human mammal having incorporated into its genome an expression construct in which nucleic acid encoding an oncogene is operably linked to an inducible promoter; the mammal further has a genetic mutation that causes it to have an increased susceptibility to cancer.

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Patent Owner(s)

  • DANA-FARBER CANCER INSTITUTE, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chin, Lynda Boston, MA 28 205
DePinho, Ronald A Boston, MA 43 278

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