Treatment or prevention of cardiovascular events via the administration of a colchicine derivative

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United States of America Patent

PATENT NO 11944594
APP PUB NO 20230270697A1
SERIAL NO

18144470

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for reducing a risk of at least one cardiovascular event in a subject in need thereof, which includes administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the at least one cardiovascular event is chosen from myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death; wherein the subject has no contra-indications to colchicine therapy, and has at least one risk factor; and vii. therapy with at least one drug chosen from aspirin, clopidogrel, statins, beta blockers, calcium blockers, and ACE inhibitors; and wherein the composition reduces the risk of the subject experiencing the at least one cardiovascular event by a greater percentage than a composition that does not include colchicine or the pharmaceutically acceptable salt thereof.

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Patent Owner(s)

  • MURRAY AND POOLE ENTERPRISES LTD

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Nidorf, Mark Menora, AU 15 11

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