Method for noncovalently immobilizing a biomolecule on a solid substrate and microarray produced according to the method
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United States of America Patent
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Nov 3, 2009
Grant Date -
Aug 18, 2005
app pub date -
Feb 7, 2005
filing date -
Feb 16, 2004
priority date (Note) -
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Abstract
Provided is a method for noncovalently immobilizing a biomolecule on a solid substrate, including: providing a solid substrate having a first functional group attached thereto, the first functional group having a hydrogen bond donating ability; and reacting a mixture of a compound having a hydrogen bond accepting ability and a biomolecule functionalized with a second functional group, with the surface of the substrate, the second functional group having a hydrogen bond donating ability, in order to noncovalently immobilize the biomolecule on the substrate.
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