Peptides for detecting antibodies to HTLV-2
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United States of America Patent
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Sep 23, 1997
Grant Date -
N/A
app pub date -
Apr 17, 1995
filing date -
Nov 13, 1989
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Peptides corresponding to epitopes of HTLV-2 proteins are provided. These peptides are immunologically reactive with HTLV-2 specific antibodies. Several of the peptides are sufficiently unreactive to antibodies to HTLV-1 to distinguish between antibodies which recognize HTLV-1 and those which recognize HTLV-2. Thus HTLV-1 infections can be distinguished from HTLV-2 infections. The peptides are useful in assays for detection of HTLV-2 infection or exposure. The peptides are also useful as vaccine compositions against HTLV-2. Antibodies generated in response to immunization by the peptides are also provided.
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