Truncated von Willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder

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United States of America Patent

PATENT NO 11890327
SERIAL NO

16349002

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Abstract

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The invention pertains to a recombinant polypeptide comprising a truncated von Willebrand Factor (VWF) for use in the treatment or prophylaxis of a blood coagulation disorder, said treatment or prophylaxis comprising administering the recombinant polypeptide and a Factor VIII protein (FVIII) extravascular to a subject having a blood coagulation disorder, wherein said recombinant polypeptide is capable of binding to said FVIII, and wherein the molar ratio of the recombinant polypeptide to be administered to the FVIII to be administered is higher than 50.

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Patent Owner(s)

Patent OwnerAddress
CSL BEHRING LENGNAU AG2543 LENGNAU BE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Pestel, Sabine Marburg, DE 38 242
Raquet, Elmar Frankenberg, DE 1 0
Weimer, Thomas Gladenbach, DE 56 598

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