Method for controlling hemophilia in mammals

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United States of America Patent

PATENT NO 4536392
SERIAL NO

06508213

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method for controlling HemophiliaA (Antihemophilic Factor (F. VIII:C) deficiency) in mammals is described. Factor VIII:C deficiency in the mammal is bypassed by infusion of a synergistic mixture of a phospholipid and Factor Xa so that the cascade process of blood clotting may continue. The proportions of phospholipid and Factor Xa in the mixture are critical as too little Xa has no effect while too much is toxic (thrombogenic).

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Patent Owner(s)

  • QUEEN'S UNIVERSITY AT KINGSTON;QUEEN'S UNIVERSITY OF KINGSTON, A CORP. OF CANADA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Giles, Alan R Kingston, CA 3 25
Mann, Kenneth G Rochester, MN 29 329

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