Biochemical amplification of nucleic acids
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United States of America Patent
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Jul 24, 2007
Grant Date -
Feb 12, 2004
app pub date -
Aug 7, 2002
filing date -
Aug 7, 2002
priority date (Note) -
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Abstract
A method of cleaning a pin head or other implements between handling a plurality of samples of nucleic acid subject to an amplification process using a biochemical amplification product. The method comprises exposing the pin head or other implement to ultraviolet (UV) and preferably also infrared (IR) illumination between handling different samples in order to suppress cross-contamination by non-specific amplification. The biochemical amplification product may be obtained from a rolling circle amplification (RCA) procedure, such as that catalyzed by bacteriophage phi29, or a polymerase chain reaction (PCR) amplification product.
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