Methods and materials for treating cancer

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United States of America Patent

PATENT NO 11497729
APP PUB NO 20210283101A1
SERIAL NO

16316182

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Abstract

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This document provides methods and materials involved in treating cancer. For example, methods and materials for using an inhibitor of USP7 polypeptide to increase the sensitivity of cancer cells (e.g., CD340+ cancer cells such as HER2+ cancer cells) to treatment with an inhibitor of a CD340 polypeptide (e.g., an inhibitor of a HER2 polypeptide) are provided. Methods and materials for using USP7 polypeptide inhibitors in combination with CD340 polypeptide inhibitors to treat cancer (e.g., HER2+ breast cancer that was refractory to trastuzumab alone treatment) are provided.

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Patent Owner(s)

  • MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boughey, Judy C Rochester, US 3 0
Goetz, Matthew P Rochester, US 9 3
Qin, Bo Rochester, US 41 305
Wang, Liewei Rochester, US 11 6
Yu, Jia Rochester, US 124 1189

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