Glycoprotein synthesis
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United States of America Patent
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Jul 3, 2007
Grant Date -
Dec 1, 2005
app pub date -
Dec 14, 2004
filing date -
Oct 16, 2002
priority date (Note) -
Expired
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Abstract
Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.
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