Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of acids

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United States of America Patent

PATENT NO 9981935
SERIAL NO

14902661

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Abstract

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The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of a specific type and of at least one Bransted acid or in the presence a specific chiral compound having a Bransted acid functional group in the molecule.

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  • DSM IP ASSETS B. V.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bonrath, Werner Basel, CH 144 72
Letinois, Ulla Basel, CH 18 0
Medlock, Jonathan Alan Basel, CH 36 20
Netscher, Thomas Basel, CH 52 27

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