Method and composition for treating vascular graft occlusion
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United States of America Patent
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Jul 15, 1997
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N/A
app pub date -
Jun 2, 1995
filing date -
Apr 6, 1990
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Abstract
The invention provides RGD containing peptides which are cyclized and contain hydrophobic moieties adjacent the carboxy terminus of the RGD sequence. Such peptides have an high affinity for the receptor IIb/IIIa and low affinity for the fibronectin and vitronectin receptors. Such peptides can be administered in a suitable physiologically acceptable carrier to therapeutically treat thrombosis.
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