Modification of D- and T-arms of tRNA enhancing D-amino acid and β-amino acid uptake

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United States of America Patent

PATENT NO 11946042
APP PUB NO 20200308572A1
SERIAL NO

16755942

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Abstract

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The purpose of the present invention is to provide, for translation in a cell-free translation system, a novel translation system capable of synthesizing a peptide having therein consecutive non-proteinogenic amino acids. The present invention provides a tRNA containing the base sequence represented by SEQ ID NO: 1 and encoding a non-proteinogenic amino acid.

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Patent Owner(s)

  • THE UNIVERSITY OF TOKYO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Katoh, Takayuki Tokyo, JP 57 994
Suga, Hiroaki Tokyo, JP 41 158

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