Oligonucleotide analogues targeting human LMNA

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United States of America Patent

PATENT NO 11802283
APP PUB NO 20210010001A1
SERIAL NO

17024100

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Abstract

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Provided are LMNA-targeted antisense oligonucleotides for reducing expression of one or more aberrantly spliced LMNA mRNA isoforms that encode progerin.

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Patent Owner(s)

Patent OwnerAddress
PROGERIA RESEARCH FOUNDATION INCP O BOX 3453 PEABODY MA 01961

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bestwick, Richard Keith Cambridge, US 18 156
Cao, Kan Bowie, US 8 53
Collins, Francis S Bethesda, US 32 509
Erdos, Michael R Bethesda, US 5 53
Gordon, Leslie B Foxboro, US 17 33
Kole, Ryszard Cambridge, US 51 1723

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