Memory tests using item-specific weighted memory measurements and uses thereof
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United States of America Patent
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Jul 4, 2006
Issued Date -
N/A
app pub date -
Aug 28, 2003
filing date -
Aug 6, 1999
priority date (Note) -
Expired
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Abstract
This invention relates to a method for increasing the usefulness, sensitivity and specificity of tests that measure memory and facets of memory, including learning, retention, recall and/or recognition. Specifically, the sensitivity and specificity of such tests are enhanced by selectively weighting the value of specific items recalled by the test subject, either by weighting such items within any specific testing trial or across numerous testing trials. Also disclosed are various methods of reducing ceiling effects in memory tests. The invention also provides improved tests which employ item-specific weighting for the diagnosis of Alzheimer's Disease and other dementia characterized by memory impairment, as well as a method of screening for and evaluating the efficacy of potential therapeutics directed to the treatment of such dementia.
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