Essential bacterial genes and their use

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United States of America Patent

PATENT NO 6627747
SERIAL NO

09393858

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Abstract

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Disclosed are two genes, termed 'yphC' and 'yqjK,' found in Streptococcus pneumoniae, which are essential for survival for a wide range of bacteria. These genes and the essential polypeptides that they encode, as well as homologs and orthologs thereof, can be used to identify antibacterial agents for treating a broad spectrum of bacterial infections.

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Patent Owner(s)

  • MILLENNIUM PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fritz, Christian Natick, MA 43 330
Guzman, Luz-Maria Boston, MA 16 7
Youngman, Philip Boston, MA 15 15

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