Anti-ICOS antibodies

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United States of America Patent

PATENT NO 11858996
APP PUB NO 20190330345A1
SERIAL NO

16323980

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, including species cross-reactive antibodies, using transgenic knock-out mice.

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Patent Owner(s)

  • KYMAB LIMITED

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ali, Mohammed Hanif Cambridge, GB 9 44
Arkinstall, Stephen John Cambridge, GB 15 58
Borhis, Gwenoline Cambridge, GB 2 0
Campbell, Jamie Iain Cambridge, GB 13 41
Germaschewski, Volker Cambridge, GB 46 299
Kirby, Ian Cambridge, GB 61 641
Kosmac, Miha Cambridge, GB 32 250
Lee, E-Chiang Cambridge, GB 113 1935
McCourt, Matthew John Cambridge, GB 12 51
Parveen, Nahida Cambridge, GB 3 8
Rowlands, Robert Cambridge, GB 2 7
Sainson, Richard Charles Alfred Cambridge, GB 14 53

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