Intercalating fluorescent dyes for labelling nucleic acids and preparation method thereof
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United States of America Patent
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Jun 6, 2023
Grant Date -
Jul 1, 2021
app pub date -
Dec 19, 2020
filing date -
Dec 26, 2019
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Abstract
The novel intercalating fluorescent compounds of exemplary embodiments of the present invention for analyzing nucleic acids, etc. have excellent intercalating efficiency with nucleic acids such as DNA and RNA of biomaterials, and may not only continuously maintain fluorescence properties and efficiency, but also have excellent effects even in terms of storage stability such as temperature and moisture, etc. and biosafety. In addition, the fluorescent compounds have various advantages capable of being dissolved in distilled water, which is a solvent harmless to the human body, and being applied to a wide range of analysis without being limited to the analysis of specific cells and living tissues.
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