Process for the production of a crystalline glucagon receptor antagonist compound

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United States of America Patent

PATENT NO 8232413
APP PUB NO 20100184995A1
SERIAL NO

12675990

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Abstract

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The present invention relates to a process for the production of crystalline particles of a glucagon receptor antagonist compound. The process includes the steps of generating microseeds and subjecting the microseeds to a crystallization process. The resulting crystalline particles have a mean particle size of less than about 100 mm. The present invention also provides for a pharmaceutical composition which includes the crystalline particles produced by the method described herein and a pharmaceutically acceptable carrier.

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Patent Owner(s)

  • MERCK SHARP & DOHME CORP.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cohen, Benjamin M Cranford, US 27 230
Cote, Aaron S West Windsor, US 12 87
Kumke, Daniel J Colts Neck, US 5 31
Tan, Lushi Edison, US 24 62

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