Immunoglobulin chimeric monomer-dimer hybrids

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United States of America Patent

PATENT NO 11168125
SERIAL NO

16518642

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Abstract

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The invention relates to a chimeric monomer-dimer hybrid protein wherein the protein comprises a first and a second polypeptide chain, the first polypeptide chain comprising at least a portion of an immunoglobulin constant region and a biologically active molecule, and the second polypeptide chain comprising at least a portion of an immunoglobulin constant region without the biologically active molecule of the first chain. The invention also relates to methods of using and methods of making the chimeric monomer-dimer hybrid protein of the invention.

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Patent Owner(s)

  • BIOVERATIV THERAPEUTICS INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bitonti, Alan J Acton, US 63 1684
Low, Susan C Pepperell, US 14 765
Mezo, Adam R Waltham, US 25 953
Peters, Robert T Needham, US 71 1614
Rivera, Daniel S Providence, US 35 1037

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