3-heteroaryl-3,5-dihydro-4-oxo-4H-pyridazino[4,5-b] indole-1-acetamide derivatives, preparation and use thereof in medicaments

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United States of America Patent

PATENT NO 7235554
APP PUB NO 20050124615A1
SERIAL NO

10509695

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Abstract

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The invention provides compounds of general formula (I) ##STR00001## in which X represents a hydrogen or halogen atom; R.sub.1 represents a hydrogen atom or a (C.sub.1-C.sub.4)alkyl group; R.sub.2 and R.sub.3 each independently of one another represent a hydrogen atom or a (C.sub.1-C.sub.4)alkyl group, or else R.sub.2 and R.sub.3, together with the nitrogen atom bearing them, form a pyrrolidinyl, piperidinyl, morpholinyl or 4-(C.sub.1-C.sub.4)alkylpiperazinyl group; and Het represents a heteroaromatic group of pyridinyl, quinolinyl, isoquinolinyl, pyrimidinyl, pyrazinyl or pyridazinyl type which may carry one or more halogen atoms and/or one or more (C.sub.1-C.sub.4)alkyl and/or (C.sub.1-C.sub.4)alkoxy groups; in the form of bases, addition salts with acids, solvates or hydrates; the pharmaceutical compositions comprising them, processes for preparing them, and synthesis intermediates.

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Patent Owner(s)

  • SANOFI;SANOFI-SYNTHELABO

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Froissant, Jacques Moree, FR 31 107
Marabout, Beno Massy, FR 4 8
Marguet, Frank Verrieres le Buisson, FR 21 60
Puech, Free La Celle Saint Cloud, FR 2 4

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