Immunisation of large mammals with low doses of RNA

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United States of America Patent

PATENT NO 11851660
APP PUB NO 20230112809A1
SERIAL NO

18065267

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Abstract

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RNA encoding an immunogen is delivered to a large mammal at a dose of between 2 μg and 100 μg. Thus the invention provides a method of raising an immune response in a large mammal, comprising administering to the mammal a dose of between 2 μg and 100 μg of immunogen-encoding RNA. Similarly, RNA encoding an immunogen can be delivered to a large mammal at a dose of 3 ng/kg to 150 ng/kg. The delivered RNA can elicit an immune response in the large mammal.

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Patent Owner(s)

Patent OwnerAddress
GLAXOSMITHKLINE BIOLOGICALS SARIXENSART

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Geall, Andrew Littleton, US 92 3354

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