High-resolution confocal microscope

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11307397
APP PUB NO 20210373306A1
SERIAL NO

16650252

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Abstract

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A method for the high-resolution scanning microscopy of a specimen where the specimen is illuminated with illuminating radiation such that the illuminating radiation is focused to a diffraction-limited illuminating spot at a point in or on the specimen. The point is projected in a diffraction-limited manner in a diffraction image onto a flat panel detector having pixels. The flat panel detector, owing to the pixels thereof, have a spatial resolution which resolves a diffraction structure of the diffraction image. The point is shifted relative to the specimen into different scanning positions by an increment which is smaller than the diameter of the illuminating spot and a 3D image is generated. The pixels of the flat panel detector are divided into groups. A pre-calculated raw image is calculated for each group and are unfolded three-dimensionally to generate the image of the specimen.

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Patent Owner(s)

  • CARL ZEISS MICROSCOPY GMBH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bathe, Wolfgang Jena, DE 19 97
Kalinin, Stanislav Weimar, DE 11 5

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