Human monoclonal antibody with specificity for Dengue virus serotype 1 E protein and uses thereof

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United States of America Patent

PATENT NO 9376486
APP PUB NO 20130259871A1
SERIAL NO

13993983

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Abstract

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Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.

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Patent Owner(s)

  • DSO NATIONAL LABORATORIES;NATIONAL UNIVERSITY OF SINGAPORE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hanson, Brendon John Singapore, SG 4 50
Kukkaro, Petra Eveliina Singapore, SG 2 6
Lim, Angeline Pei Chiew Singapore, SG 2 6
Lok, Shee Mei Singapore, SG 2 6
Macary, Paul Anthony Singapore, SG 6 57
Ng, Mah Lee Mary Singapore, SG 5 6
Teo, En Wei Singapore, SG 2 6
Teoh, Ee Ping Evelyn Singapore, SG 2 6

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