Methods and compositions for RNA-guided treatment of HIV infection

Number of patents in Portfolio can not be more than 2000

United States of America

PATENT NO 11285193
APP PUB NO 20180236042A1
SERIAL NO

15882207

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Abstract

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A method of treating a subject at risk for having a virus infection, by administering to the subject a prophylactically effective amount of a composition comprising a vector encoding a CRISPR-associated endonuclease and at least two guide RNAs, wherein the guide RNAs are complementary to two target sequences spanning from the 5′- to 3′-LTRs of the sequence in the virus, and preventing a retroviral infection.

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Patent Owner(s)

  • TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hu, Wenhui Cherry Hill, US 47 207
Khalili, Kamel Bala Cynwyd, US 73 189

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