Angiogenesis inhibitors and uses thereof
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United States of America Patent
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Apr 2, 2002
Grant Date -
N/A
app pub date -
Aug 19, 1999
filing date -
Aug 20, 1998
priority date (Note) -
Expired
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Abstract
The present invention features isolated angiogenesis inhibitors having a molecular weight of between about 40 kDa to 50 kDa and having an amino acid sequence substantially similar to that of the amino acid sequence shown in SEQ ID NO. 2 or SEQ ID NO. 3. Further provided are methods of making and using the angiogenesis inhibitors, e.g., to inhibit vascularization or to block osteonectin and plasminogen interaction.
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