Carbon nanotube anchor for mass spectrometer
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United States of America Patent
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Dec 3, 2013
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N/A
app pub date -
Mar 5, 2009
filing date -
Mar 5, 2008
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Abstract
This invention enables a sensitivity enhancement in the detection of molecular compounds. A mass spectrometry analyte support with nanotube anchors are used to concentrate MALDI samples, specifically samples prepared with water-insoluble matrix compounds, on the anchor spot. The surface structure is established through patterned carbon nanotube anchor growth, providing a nucleation center for analyte and reducing sample precipitation on the surrounding MALDI wafer. Also disclosed is a method of creating a mass spectrometry support using patterned metal catalyst to grow carbon nanotubes. The carbon nanotubes enhance nucleation on specific areas of a sample plate to concentrate analyte/matrix deposit during droplet evaporation.
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