Polypeptide compositions comprising spacers

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United States of America Patent

PATENT NO 11771718
APP PUB NO 20190111080A1
SERIAL NO

16163233

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Disclosed herein are methods and compositions including antigen-binding polypeptides comprising a stalk region and a stalk extension region. In some cases, the antigen-binding compositions comprising the stalk extension region has increased expression on a cell surface and, in some cases, has increased antigen-binding efficiency. A subject antigen binding polypeptide can be a chimeric antigen receptor (CAR).

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Patent Owner(s)

  • PRECIGEN, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Shah, Rutul R Blacksburg, US 7 10

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