Loteprednol and moxifloxacin compositions and methods

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United States of America Patent

PATENT NO 11382910
SERIAL NO

17458532

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Abstract

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Provided here are new ophthalmologically suitable pharmaceutical compositions comprising an effective amount of a moxifloxacin compound and an effective amount of a loteprednol compound. In aspects, the compositions are stable suspensions, which maintain physical stability and chemical stability for extended periods of time (e.g., exhibiting no sustained flocculation, coagulation, or clumping after several months of storage under typical storage conditions). In aspects, the compositions are suspensions that include a suspension component comprising one or more suspension agents. In aspects, the suspension component includes an ionic suspension agent. In aspects, the composition also or alternatively comprises a non-ionic surfactant, non-ionic suspension agent, or both, or an agent that provides both functions. In aspects, such compositions further comprise an effective amount of a chelating agent/component. Further described are related compositions and methods of making and using such compositions, e.g., in the treatment of eye infections.

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Patent Owner(s)

  • SOMERSET THERAPEUTICS LLC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Shah, Mandar V Rockaway, US 75 173
Subramanian, Ilango Warren, US 49 6
Subramanian, Veerappan Warren, US 53 16
Trehan, Aman Somerset, US 38 30

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