Nucleophilic substitution process
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United States of America Patent
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Apr 16, 1985
Issued Date -
N/A
app pub date -
Mar 10, 1983
filing date -
Apr 30, 1982
priority date (Note) -
Expired
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Abstract
Nitrophenoxy- or nitrophenylthiobenzeneacetic acid esters are prepared by reacting a nitrophenoxy- or nitrophenylthiobenzene with an alpha,alpha-disubstituted acetic acid ester in an inert solvent and in the presence of a base. The products are useful as intermediates for the synthesis of pharmaceuticals, such as fenoprofen.
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