Fatty acid esters of lactic acid salts as permeation enhancers
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United States of America Patent
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Sep 14, 1999
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app pub date -
Oct 29, 1997
filing date -
Oct 30, 1996
priority date (Note) -
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Abstract
A transdermal drug delivery system which enhances the delivery of the drug comprises a composition containing, as an enhancer, one or more C.sub.6 to C.sub.22 fatty acid esters of a lactic acid salt. These compositions are made up of a safe and effective amount of an active pharmaceutical permeant contained in a penetration-enhancing vehicle comprising, 0.25 to 50% w. of the fatty acid ester of a lactic acid salt enhancer in a suitable pressure sensitive adhesive carrier vehicle formed from and aqueous emulsion based pressure sensitive adhesive.
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