Antitumor agent
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United States of America Patent
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-
Jun 4, 1985
Grant Date -
N/A
app pub date -
May 20, 1981
filing date -
May 22, 1980
priority date (Note) -
Expired
status (Latency Note)
Importance
Abstract
An antitumor agent comprising a combination of 5-fluorocytosine and cytosinedeaminase has been developed. As to the practical administration procedure of the agent, it is preferable to carry out in such a manner that 5-fluorocytosine is first administered in any portion of the body, and cytosinedeaminase is then administered into the topically suffered portion. The administered 5-fluorocytosine is transferred into the suffered portion, and the 5-fluorocytosine is affected with the action of cytosinedeaminase to convert the former compound into 5-fluorouracil, resulting in that the necrosis of the tumor tissue is caused.
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