Tyrosylated proinsulin C-peptide derivatives
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United States of America Patent
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Apr 27, 1982
Grant Date -
N/A
app pub date -
Nov 27, 1979
filing date -
Oct 2, 1978
priority date (Note) -
Expired
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Abstract
The disclosed peptide derivative of the formula: Y--Tyr--Gly--R Wherein, Y represents a hydrogen atom or an amino protecting group, Tyr represents a tyrosine residue wherein at least one of the hydrogen atoms on the phenyl ring may be substituted by a radioactive iodine, Gly represents a glycine residue, and R represents a peptide residue corresponding to an amino acid sequence which includes at least positions 7 through 21 of human proinsulin C-peptide proves to be useful for determining C-peptide level in human serum.
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