Method for using lipoprotein associated coagulation inhibitor to treat sepsis
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United States of America Patent
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-
May 16, 2000
Issued Date -
N/A
app pub date -
Jun 7, 1995
filing date -
Jun 1, 1992
priority date (Note) -
Expired
status (Latency Note)
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Abstract
A method for prophylactically or therapeutically treating sepsis or septic shock is described, wherein an inhibitor to tissue factor is administered to septic patients. Additionally, a method for treating inflammation is described wherein the inhibitor is administered to pateints. This inhibitor is termed lipoprotein associated coagulation inhibitor, or commonly LACI. It is 38 kD and has 276 amino acids. LACI has now been shown to be useful for the treatment of sepsis, septic shock and inflammation.
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