High load formulations and methods for providing prolonged local anesthesia
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United States of America Patent
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Jul 13, 1999
Issued Date -
N/A
app pub date -
Sep 16, 1996
filing date -
Sep 10, 1992
priority date (Note) -
Expired
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Abstract
A formulation for inducing sustained local anesthesia in a patient comprising a substrate comprising a high load of local anesthetic by weight and an effective amount of a biocompatible, controlled release material to obtain a reversible nerve blockade or anesthesia effect when implanted or injected in a patient, and a non-toxic glucocorticosteroid agent effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without the glucocorticosteroid agent.
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