Peritoneal dialysis solution containing modified icodextrins
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United States of America Patent
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Aug 3, 2004
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N/A
app pub date -
Dec 4, 1998
filing date -
Dec 4, 1998
priority date (Note) -
Expired
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Abstract
The present invention provides a peritoneal dialysis solution that contains heat stable osmotic agents such as D-glucitols, gluconic acids and alkylglycosides produced the reduction, oxidation or glycosylation of icodextrins respectively. As a result, osmotic agents that are stable under autoclaving or heat sterilization conditions are provided which reduces the amount of bioincompatible materials in the sterilized peritoneal dialysis solutions. Methods of preparing the D-glucitols, gluconic acids and alkylglycosides are disclosed.
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