Methods and compositions for simultaneous editing of both strands of a target double-stranded nucleotide sequence

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United States of America Patent

PATENT NO 11912985
APP PUB NO 20230220374A1
SERIAL NO

18053269

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Abstract

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The present disclosure provides systems, compositions, and methods for simultaneously editing both strands of a double-stranded DNA sequence at a target site to be edited. Further provided herein are pharmaceutical compositions, polynucleotides, vectors, cells, and kits for simultaneously editing both strands of a double-stranded DNA sequence.

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Patent Owner(s)

  • THE BROAD INSTITUTE, INC.; PRESIDENT AND FELLOWS OF HARVARD COLLEGE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Anzalone, Andrew Vito Cambridge, US 11 30
Gao, Xin Cambridge, US 105 360
Levy, Jonathan Ma Cambridge, US 5 78
Liu, David R Cambridge, US 206 8026
Podracky, Christopher J Cambridge, US 2 2

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