Spheron component peptides and pharmaceutical compositions
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United States of America Patent
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Apr 7, 2009
Grant Date -
Feb 12, 2004
app pub date -
May 23, 2003
filing date -
Mar 4, 2002
priority date (Note) -
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Abstract
The present invention relates to racemized proteins and racemized protein components of spherons that are useful for identifying compounds capable of preventing and/or ameliorating symptoms of Alzheimer's Disease and/or dementia associated with cerebral amyloidosis. The invention also relates to the compounds identified by the methods, and methods of treating and/or ameliorating symptoms of Alzheimer's Disease and/or dementia associated with cerebral amyloidosis. The invention also relates to methods of making an Alzheimer's Disease or dementia associated with cerebral amyloidosis animal model or test animal, the animal model produced therefrom, and to a method of using the animal model to screen for effective therapies.
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