Sesquiterpenoid analogs

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United States of America Patent

PATENT NO 11518770
SERIAL NO

16531185

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Abstract

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The present disclosure relates to novel sesquiterpenoid compounds as SHP2 and/or POLE3 inhibitors for potential treatment for cancers, and to methods of making and using the sesquiterpenoid compounds. The present invention therefore provides a method of using the disclosed compounds as chemosensitizations agent to a DNA damaging drugs for cancers.

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Patent Owner(s)

  • PURDUE RESEARCH FOUNDATION; THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adibekian, Alexander Palm, US 4 9
Dai, Mingji West Lafayette, US 22 20
Davis, Dexter Cameron West Lafayette, US 6 5
Hoch, Dominic Gregor Jupiter, US 2 0
Zhang, Zhong-Yin West Lafayette, US 18 26

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