Use of TRAIL polypeptides to induce apoptosis
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United States of America Patent
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Jun 15, 2010
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app pub date -
Aug 21, 2008
filing date -
Jun 29, 1995
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Abstract
A novel cytokine designated TRAIL induces apoptosis of certain target cells, including cancer cells and virally infected cells. Isolated DNA sequences encoding TRAIL are disclosed, along with expression vectors and transformed host cells useful in producing TRAIL polypeptides. Antibodies that specifically bind TRAIL are provided as well.
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