Peptide quantitation assay for differentiating full-length high molecular weight kininogen (HMWK) and cleaved HMWK

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United States of America Patent

PATENT NO 11668718
APP PUB NO 20210025898A1
SERIAL NO

16062734

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Abstract

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Methods for differentiating full-length high molecular weight kininogen (HMWK) and cleaved HMWK in a sample are provided herein. Such methods may comprise treating a biological sample with a protease to generate a plurality of digested peptides, and measuring one or more signature peptides, which are indicative of cleaved HMWK and/or full-length HMWK.

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TAKEDA PHARMACEUTICAL COMPANY LIMITEDOSAKA-SHI OSAKA 541-0045

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Faucette, Ryan Melrose, US 19 74
Mustafa, Gul M Morgantown, US 2 0
Sexton, Daniel J Melrose, US 58 510
Szewc, Mark Morgantown, US 2 0
Wu, Jiang Lexington, US 111 1725
Zhang, Guodong Lexington, US 714 17509

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