Diagnostic methods using plasmon resonant particles
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United States of America Patent
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Jul 19, 2011
Grant Date -
Jun 25, 2009
app pub date -
Mar 5, 2009
filing date -
Feb 20, 1997
priority date (Note) -
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Abstract
A method and apparatus for interrogating a target having a plurality of plasmon resonant particles (PREs) distributed in the target are disclosed. In the method, a field containing the target is illuminated, and one or more spectral emission characteristics of the light-scattering particles in the field are detected. From this data, an image of positions and spectral characteristic values in the field is constructed, allowing PREs with a selected spectral signature to be discriminated from other light-scattering entities, to provide information about the field. Also disclosed are a novel PRE composition for use in practicing the method, and a variety of diagnostic applications of the method.
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