Self-calibrating gradient dilution in a constituent assay and gradient dilution apparatus performed in a thin film sample
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United States of America Patent
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Jul 17, 2012
Grant Date -
Oct 8, 2009
app pub date -
Apr 2, 2009
filing date -
Apr 2, 2008
priority date (Note) -
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Abstract
A method and apparatus for measuring antibody titers in a thin film sample in an automated system which does not require multiple dilutions. The system provides a simple method for creating an in-situ dilution within a sample analysis chamber without the use of any precision fluid-handling components, and further, to use the same principles to provide a wide range of sample dilutions within the chamber so as to obviate the need for additional dilution steps when dealing with samples possibly containing wide ranges of analyte concentrations.
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