Bio-production of lentiviral vectors

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United States of America Patent

PATENT NO 10138495
APP PUB NO 20180112233A1
SERIAL NO

15802363

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Abstract

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The present disclosure provides a method of generating a stable producer cell line. The generation of stable producer cell lines, such as those provided in accordance with the present invention, increases the reproducibility and ease of creating high titer lentiviral stocks while easing biosafety concerns and the variation in expressed envelope proteins defines the tropism of the generated virus. The present disclosure also provides for a novel lentiviral transfer vector plasmid.

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Patent Owner(s)

Patent OwnerAddress
CALIMMUNE INC5151 E BROADWAY BLVD SUITE 700 TUCSON AS 85711

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bartlett, Jeffrey S Columbus, US 16 354
Lee, Chi-Lin Arcadia, US 11 5

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