Method to inhibit airway hyperresponsiveness using aerosolized T cell receptor antibodies

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United States of America Patent

PATENT NO 8178098
APP PUB NO 20020172677A1
SERIAL NO

09826319

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Abstract

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Disclosed is a method to reduce airway hyperresponsivesness in an animal by the direct delivery to the lungs of aerosolized antibodies against T cell receptors. The method is particularly useful for treating airway hyperresponsiveness associated with allergic inflammation, is effective at extremely low doses of antibody, and does not have a substantial effect on the peripheral immune system.

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Patent Owner(s)

  • NATIONAL JEWISH HEALTH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Born, Willi K Denver, US 9 42
Gelfand, Erwin Englewood, US 11 50
Kanehiro, Arihiko Okayama, JP 7 46
Lahn, Michael F Zionsville, US 5 35

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