Cytotoxic T lymphocyte activation assay
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United States of America Patent
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Jan 19, 1993
Issued Date -
N/A
app pub date -
Nov 8, 1990
filing date -
Jan 5, 1988
priority date (Note) -
Expired
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Abstract
A method is provided for the quantitative study of cytotoxic T-lymphocyte activation by measuring secreted granule-associated BLT esterase activity after incubating the cytotoxic T-lymphocytes with activating stimuli. This method can be used to screen inhibiting (drugs) or activating agents (monoclonal antibodies) (at selected sub-optimal levels of activation of cytotoxic T-lymphocytes.
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