Pyrrolopyrrolone derivatives as inhibitors of neutrophil elastase
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United States of America Patent
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Nov 30, 1999
Grant Date -
N/A
app pub date -
Sep 25, 1998
filing date -
Mar 28, 1996
priority date (Note) -
Expired
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Abstract
There are described according to the invention compounds of formula (I) (relative stereochemistry indicated), wherein R.sub.1, R.sub.2, R.sub.3 and X are as defined in the specification, together with processes for preparing them, compositions containing them and their use as pharmaceuticals. Compounds of formula (I) are indicated inter alia for the treatment of chronic bronchitis.
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