Anti-B7-H3 antibody and use thereof

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United States of America Patent

PATENT NO 11891445
SERIAL NO

17057643

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Abstract

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Provided is an anti-B7-H3 antibody specifically recognizing a B7-H3, which can be usefully as a cancer therapeutic agent, as having an inhibitory activity of an immune checkpoint which induces antibody-dependent cell-mediated cytotoxicity and T cell activation inhibited by B7-H3. In particular, the antibody having the inhibitory activity of an immune checkpoint can be used in combination with other immunoantibody therapeutic agents. In addition, it can be usefully used for cancer targeting treatment including detection of various cancers expressing B7-H3 through specific binding to B7-H3, and drug delivery to specific cancer, etc.

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Patent Owner(s)

Patent OwnerAddress
ABL BIO INC16 DAEWANGPANGYO-RO 712BEON-GIL BUNDANG-GU SEONGNAM-SI GYEONGGI-DO 134-88 REPUBLIC OF KOREA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahn, Jinhyung Seongnam-si, KR 15 23
Chung, Hyejin Seongnam-si, KR 9 15
Ha, Sang-Jun Seongnam-si, KR 3 0
Jung, Uijung Seongnam-si, KR 3 0
Kim, Myeong Joon Seongnam-si, KR 1 0
Kim, Yeunju Seongnam-si, KR 8 0
Lee, Yangsoon Seongnam-si, KR 11 30
Pak, Youngdon Seongnam-si, KR 8 0
Park, Eunyoung Seongnam-si, KR 52 458
Park, Kyeongsu Seongnam-si, KR 4 0
Park, Kyungjin Seongnam-si, KR 14 8
Son, Yong-Gyu Seongnam-si, KR 6 0
Song, Daehae Seongnam-si, KR 10 8
Sung, Byungje Seongnam-si, KR 12 8
Sung, Eunsil Seongnam-si, KR 9 0

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