Compositions and methods for the treatment of chronic trypanosomiasis infections
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United States of America Patent
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May 26, 1981
Grant Date -
N/A
app pub date -
May 17, 1979
filing date -
May 17, 1979
priority date (Note) -
Expired
status (Latency Note)
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Abstract
Compositions comprising substituted 5-nitroimidazoles and diminazene aceturate (Berenil) useful in the treatment of chronic trypanosomiasis infections in humans and animals. The substituted 2- or 5-nitroimidazoles having a 1-alkyl substituent and a 2-substituent, the latter being a .DELTA..sup.2 -4',5'-disubstituted isoxazoline. The 4',5'-substitution on the isoxazoline moiety is a saturated alkyl ring. Method of treatment of chronic trypanosomiasis infections in humans and animals by administering said compositions.
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