Process for preparing lincomycin and clindamycin ribonucleotides
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United States of America Patent
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Feb 7, 1984
Grant Date -
N/A
app pub date -
Sep 17, 1982
filing date -
Sep 17, 1982
priority date (Note) -
Expired
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Abstract
Novel and useful ribonucleotides of analogs of the well known antibiotics lincomycin and clindamycin. These ribonucleotides are unexpectedly highly active against Streptococcus hemolyticus and Staphylococcus aureus in vivo. These ribonucleotides are prepared by using resting cell or cell-free extracts of Streptomyces rochei, NRRL 3533, or cell-free extracts of Streptomyces coelicolor, NRRL 3532.
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