Fluorescent sensing film for pH planar optode, preparation method and application

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United States of America

PATENT NO 11300510
APP PUB NO 20200300760A1
SERIAL NO

16756476

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Abstract

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The present invention provides a fluorescent dye HPTS-lipo for monitoring two-dimensional pH value, a fluorescent sensing film, and use thereof, belonging to the field of two-dimensional pH value monitoring. The fluorescence sensing film for monitoring two-dimensional pH is prepared from the fluorescent dye HPTS-lipo, and HPTS-lipo is embedded by hydrogel D4 in a preparation process. The fluorescent dye HPTS-lipo is prepared by ligating alkylamine into sulfonic acid groups of the fluorescent dye HPTS. Compared with the fluorescent dye HPTS, the pKa value of the modified fluorescent dye HPTS-lipo is significantly varied, so that the fluorescent sensing film is suitable for monitoring different pH values and meets different experimental requirements; and the fluorescent dye HPTS-lipo has better hydrophobicity, can be kept for longer time in environment, and further solves the problem of dye leakage after being embedded by the hydrogel.

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Patent Owner(s)

  • NANJING UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Fang, Wen Nanjing, CN 40 235
Hu, Xuan Nanjing, CN 16 31
Liang, Chaogen Nanjing, CN 2 2
Liu, Zhaodong Nanjing, CN 4 2
Luo, Jun Nanjing, CN 303 1389
Yin, Daixia Nanjing, CN 2 2

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